Pilots at Lufthansa have voted to go out on strike from 22:00 GMT on 1 April until 21:59 GMT on 4 April.
As a result of strike actions Lufthansa will reduce its schedule significantly.
Flights of the Lufthansa Group Airlines Eurowings, Air Dolomiti, Swiss, Austrian Airlines and Brussels Airlines are excepted from the strikes and schedule adjustments.
The necessary cancellations are currently being made. A regularly updated list of the cancelled flights is already available on Lufthansa's website.
Lufthansa is asking all passengers to check the status of their flight before setting out on their journey.
Passengers flying with Germanwings (4U) will find all relevant information here: Latest news
Travellers affected by a flight cancellation can rebook free of charge or have their ticket refunded.
Passengers travelling within Germany whose Lufthansa flights have been cancelled because of the strike can use Deutsche Bahn trains and issue their own rail voucher either under ‘My Bookings’ on Lufthansa's website or at a Lufthansa airport check-in machine.
Passengers who are affected by cancelled Germanwings domestic flights on Lufthansa documents will not be able to access a Lufthansa rail voucher themselves. They will need to go to the Germanwings counter at the airport to receive their voucher.